For thousands of years, the open palm has been a mysterious symbol of fortune and protection from evil. Used in amulet and pendants, it goes by many names: Hamsa, Hamesh, Hand of Fatima, Hand of Mary, Hand of Miriam. Connected to an ancient goddess from the Middle East, Hamsa also represents feminine energy and fertility. Whether looking up or down, and regardless of its name, the open hand is a powerful defense against negative energy. Let this talisman protect you.